Does Xyrem show up on a drug test?

Some tests can detect GHB: blood tests – up to 6-8 hours, swab tests – between 10 minutes and six hours, and urine tests – up to 12-24 hours. As GHB is known as a date rape drug, testing is crucial. … We should mention that the drug is eliminated mainly via expiration, and only 5% of the time does urine excretes the GHB.